DigitalBreastTomosynthesis/Microcalcification.m

%% Author: Aleks Prša
% Date: June, 2022
% alex.prsa@gmail.com
% =========================================================================
%{
% 
%     DESCRIPTION:
% 
%     Program for inserting microcalcifications on breast projection images.
%
%     Faculty of Mathematic and Physics
%     University in Ljubljana
%     Ljubljana, Slovenia   
%  
%}
% =========================================================================
%%                      Insertion code

close all;clear;clc

%% Load components

addpath(genpath('Functions'));
addpath(genpath('Parameters'));

if(~exist('Output','dir'))
    mkdir('Output')
end

addpath('Output');

ParameterSettings_MicroInsertion
       
% Load projection data    
path_User = userpath;
path_ProjData = uigetdir(path_User); 

if(path_ProjData == 0)
    fprintf('Cancelled by user \n');
	return;
else
    userpath(path_ProjData)       
    fprintf('Reading DICOMs   ')
    answer = '0';
    [dataProj,infoDicom] = readDicom(path_ProjData,parameter,answer);
    parameter.bitDepth = infoDicom(:,1).BitDepth;
end

% Create phantom with inserted microcalcifications
fprintf('\nPhantom...')
microData = phantom(parameter);
microData(microData<0) = eps;

microData = flip(microData, 1);                                % Phantom in accordance with coordinate system
microData = flip(microData, 2);                                % Source is on the left side

% Perform virtual imaging of microcalcifications
fprintf('\nProjections   ')
attenuationMicro = projectionMicro(microData,parameter);
attenuationMicro = flip(attenuationMicro, 2);                  % Image captured with source on the right side

%% Microcalcification insertion 

% Breast attenuation
attenuationBreast = dataProj - parameter.mu;
attenuationBreast(attenuationBreast < 0) = 0;

% Additional attenuation due to microcalcifications
microProj = attenuationBreast .* attenuationMicro + parameter.mu;

%% Save data

filestring = ['Output',filesep,'Microcalcifications',filesep,'Projections'];   
    if(~exist(filestring))
        mkdir(filestring)
    end
fprintf('\nWriting DICOM projections   ')
writeDicomProj(attenuationMicro,infoDicom,filestring,parameter);

fprintf('\nSaving projections... \n')
save(['Output',filesep,'Microcalcifications',filesep,'Microcalcifications.mat'],'microProj','-v7.3');
infoDicom = [];

fprintf('\nFINISHED - Data stored in "Microcalcification" folder\n')

beep