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@@ -1 +1,32 @@
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-This is the code by Howard used in his study of the Three Parameter Model to personalize breast cancer screening.
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+# Breast cancer screening model
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+
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+This is the code by Howard used in his study of the Three Parameter Model to personalize breast cancer screening.
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+
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+Implemented from
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+
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+R.Liu, Estimation of the three key parameters and the lead time distribution in lung cancer screening, PhD Thesis, 2017, University of Luisville, Luisville, Kentucky.
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+
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+# Usage
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+
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+```python
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+import sys
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+import os
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+import numpy
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+
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+mPath=os.path.join('path','to','cloned','code')
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+import three_parameter_screening
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+#probabilty of conversion to early cancer stage per screening interval
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+w=0.1
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+#sensitivity of the screening exam
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+beta=0.9
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+#average of the exponential distribution Q of dwell time in early cancer stage, in units of screening interval
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+mu=0.3
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+#exponential distribution
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+def Q(t):
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+ return numpy.exp(-t/mu)
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+
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+#screening intervals
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+t=numpy.linspace(0,9,10)
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+
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+three_parameter_screening.probabilty_of_clinical_incidence(beta,w,mu,t,Q)
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+```
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